Abstract：Collision reaction cell is a key means to eliminate interference from polyatomic ions in inductively coupled plasma mass spectrometry (ICP-MS). Applying SIMION software to investigate the kinetic characteristics of ions in the cell, this paper has effectively analyzed the factors which influenced the efficiency of collision cell. The simulation showed that, under standard mode of collision reaction cell, the maximal shift radius of ions directly affected instrument signal intensity, and if q value(the value of radio frequency)and radio frequency pressure were difinited, the focus effect of different ions were similar when detected at different frequency. Under the collision mode of the cell, focusing effect occurred during the collision of ions, which induced a decrease on the passing rate of ions and diminish of signal intensity. The energy collision loss of different-radius ions was also different, which was more obvious at low pressure. It was proper to adopt kinetic discrimination effect to remove the interference from byproducts. The simulation results were consistent with the experiment, indicating that simulation could provide guidance for the optimization of instrument parameters and design of experimental parameters.
韩建华,孙传强,汪曣,赵学玒,蔡彪. 电感耦合等离子体质谱中碰撞反应池的模拟探讨[J]. 冶金分析, 2014, 34(9): 1-7.
HAN Jian-hua, SUN Chuan-qiang, WANG Yan, ZHAO Xue-hong, CAI Biao. Discussion on the simulation of collision reaction cell in inductively coupled plasma mass spectrometry. , 2014, 34(9): 1-7.
Simon M Nelms. Inductively coupled plasma mass spectrometry handbook [M]. [S.I.]:Blackwell Publishing Ltd.,2005 :12-20.
[4]
Conny hagg,Imer Szabo .New ion-optical devices utilizing oscillatory electric fields. IV. Computer simulations of the transport of an ion beam through an ideal quadrupole, hexapole, and octopole operating in the rf-only mode[J]. International Journal of Mass Spectrometry and Ion Processes,1986,73(3):295-312.
[5]
Muntean,Felician. Transmission study for rf-only quadrupoles by computer simulation[J]. International Journal of Mass Spectrometry and Ion Processes,1995,151:197-206.
[6]
Scott D Tanner,Vladimir I Baranov.A dynamic reaction cell for inductively coupled plasma mass spectrometry (ICP-DRC-MS). II. Reduction of interferences produced within the cell [J]. Journal of the American Society for Mass Spectrometry, 1999, 10(11): 1083-1094.
[7]
Dayton I E, Shoemaker F C, Mozley R F. The measurement of two-dimensional fields. Part II: study of a quadrupole magnet[J]. Review of Scientific Instruments, 1954, 25(5):485-489.
[8]
R Rao, A Bhutani. Electric hexapoles and octapoles with optimized circular section rods [J].International Journal of Mass Spectrometry, 2000,202: 31-36.
[9]
Gao C, Douglas D J. Can the effective potential of a linear quadrupole be extended to values of the Mathieu parameter q up to 0.90?[J]. Journal of the American Society for Mass Spectrometry, 2013, 24(12): 1848-1852.
[10]
Conny hagg,Imer Szabo. New ion-optical devices utilizing oscillatory electric fields. II. Stability of ion motion in a two-dimensional hexapole field[J]. International Journal of Mass Spectrometry and Ion Processes, 1986, 73(3): 237.
[11]
Conny hagg,Imer Szabo. New ion-optical devices utilizing oscillatory electric fields. III. Stability of ion motion in a two-dimentional octapole field [J].International Journal of Mass Spectrometry and Ion Processes,1986,73 (3): 277.
